Study of the Effect of N-acetylcysteine on Urinary Tract Infection in Children.
Phase 3
- Conditions
- Acute pyelonephritis.Acute tubulo-interstitial nephritis
- Registration Number
- IRCT2013112015465N1
- Lead Sponsor
- Shahid Beheshti Medical University, Faculty of Pharmacy
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 64
Inclusion Criteria
Patients between the ages of 1 and 16; Having the diagnosis of definite or probable urinary tract infection according to guidelines of pediatric infectious disease research center.
Exclusion criteria: Patients younger than 1 or older than 16 years old; Patients without the diagnosis of definite or probable urinary tract infection according to guidelines of pediatric infectious disease research center; Patients with acute/ chronic infectious or inflammatory diseases other than pyelonephritis.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum procalcitonin. Timepoint: Before giving drug, and 5 days after giving the drug. Method of measurement: Serum procalcitonin test.;CRP. Timepoint: Before and 5 days after starting therapy. Method of measurement: Blood test.;Leukocyte count. Timepoint: Before and 5 days after starting therapy. Method of measurement: Blood test.
- Secondary Outcome Measures
Name Time Method Probable adverse effects (nausea, vomiting, bad tasting, stomatitis, ...). Timepoint: Daily. Method of measurement: Clinical examination and asking from patients.