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Clinical Trials/DRKS00030602
DRKS00030602
Recruiting
Phase 4

Randomized clinical pilot study investigating the effect of Lactobacillus reuteri on subgingival biofilm formation on healing abutments and inflammatory status of surrounding peri-implant tissues - Effect of probiotics on peri-implant biofilm

Clinic of Conservative and Preventive Dentistry University of Zurich, Center of Dental Medicine0 sites28 target enrollmentOctober 26, 2022
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ConditionsTooth replacement

Overview

Phase
Phase 4
Intervention
Not specified
Conditions
Tooth replacement
Sponsor
Clinic of Conservative and Preventive Dentistry University of Zurich, Center of Dental Medicine
Enrollment
28
Status
Recruiting
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
October 26, 2022
End Date
TBD
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
Clinic of Conservative and Preventive Dentistry University of Zurich, Center of Dental Medicine

Eligibility Criteria

Inclusion Criteria

  • •Patients requiring a single implant in the posterior area (premolars and molars, maxilla or mandible) with a single\-tooth supported crown
  • •Patients 18 to 90 years of age
  • •no active periodontitis as determined by no PPD \=6mm or no periodontitis, as determined by a PSI score of \=2
  • •a full\-mouth plaque score and full\-mouth bleeding score \<25% as recorded at 6 sites per tooth
  • •\= 4 months post extraction
  • •Signed Informed Consent after being informed

Exclusion Criteria

  • •general medical condition, which represents a contraindication for implant treatment
  • •Systemic or local disease or condition that can compromise healing or osseointegration
  • •History of radiation in head\-neck area
  • •current pregnancy (captured through inquiry)
  • •\>10 Cigarettes daily
  • •Diabetes mellitus with an HbA1c \> 7
  • •antibiotic therapy within the last \= 4 weeks
  • •use of orally applied antibacterial products
  • •use of probiotic supplements
  • •use of anti\-inflammatory drugs

Outcomes

Primary Outcomes

Not specified

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