Effect of Pressure Support Ventilation During Anesthetic Emergence on Postoperative Atelectasis in Infant
试验速览
- 阶段
- 不适用
- 入组人数
- 136
- 试验地点
- 1
- 主要终点
- Frequency of atelectasis
研究概览
简要总结
Atelectasis occurs in patients of all ages who receive mechanical ventilation under general anesthesia, and although fatal cases are rare, it is known as a cause of postoperative hypoxia or fever. In pediatric patients, it has a particularly high incidence of 68-100%, and the incidence is inversely proportional to age. Pediatric patients,compared to adults, have a small capacity for functional residual capacity while a high metabolic demand, making them fundamentally vulnerable to hypoxia. Increased atelectasis during anesthesia causes hypoxia not only during anesthesia but also during recovery after anesthesia. Therefore, it is important to establish and apply a strategy to minimize the occurrence of atelectasis during mechanical ventilation under general anesthesia in pediatric patients. The aim of this study is to investigate whether pressure support ventilation at emergence period could reduce the incidence of postoperative atelectasis in infants undergoing surgery under general anesthesia.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 0 Years 至 1 Year（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •infant patients aged 0 day to 13 month
- •American Society of Anesthesiologists (ASA) classification 1~2 who are scheduled for elective surgery under general anesthesia
排除标准
- •patients with symptomatic bronchopulmonary dysplasia
- •patients with uncorrected congenital heart or pulmonary disease
- •Hemodynamically unstable requiring preoperative vasopressor administration
- •fever (>37.5°) or URI symptoms on the day of surgery
结局指标
主要结局
Frequency of atelectasis
时间窗: Within 5 minutes of arriving at the recovery room
Immediately after arriving at the recovery room, lung ultrasound is performed to check for atelectasis.
次要结局
- Frequency of atelectasis(After 30 minutes of stay in the recovery room)
- scoring of atelectasis(at the time of admission and after 30 minutes of stay in the recovery room)
- Frequency of desatuation(at the time of admission and after 30 minutes of stay in the recovery room)