Psychological and Biological Effects of Intensive Mindfulness Meditation on Offenders With Dangerous and Severe Personality Disorder: A Randomised Controlled Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 60
- 主要终点
- Change from baseline emotional regulation
研究概览
简要总结
The investigators aim to explore the psychobiological effects of a 5-day meditation intervention on offenders within dangerous and severe personality disorders (DSPD) unit at HMP Whitemoor. DSPD unit accommodates offenders with psychopathy or with two or more personality disorders. DPSD unit provides them with a 5-year rehabilitation programme that consists of group and individual therapy and aims to improve their self-regulation.
This project includes a total of 60 participants and has two major methodological innovations. First, it will include yoga as an active control group that will be matched to the meditation intervention (which means it will have the same length and the same social components) and a passive control group that will be following their usual regimen. Thus, the effects of meditation will be contrasted with another type of intervention and with not receiving any intervention.
The second methodological innovation is the combination of psychological and biological measures. Psychological measures include questionnaires (emotion regulation, mindfulness, stress) and cognitive measures (attention,empathy,behavioural control). Biological measures include EEG to measure brain activity related to empathy; gene expression and protein interlukin-6 to measure changes in immune system; and stress related hormone cortisol. The investigators also aim to determine to whom does meditation benefit the most by exploring how initial expectations of meditation, personality, mood and previous life adversity predict outcomes of meditation or yoga. The data will be collected at three time points: at baseline, immediately after and 10 weeks after the 5-day intervention.
The investigators expect that meditation and yoga will similarly improve mental and physical health. If this hypothesis are confirmed, these results will extend previous findings on the benefits of meditation and yoga to vulnerable populations, and would provide a cost-effective addition to prisoner rehabilitation.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Male offenders with dangerous and severe personality disorder aged 18-65 who will remain in the prison until at least February 2017.
排除标准
- •Major psychiatric or neurological disorders, previous meditation or yoga experience, unable to follow instructions in English,
结局指标
主要结局
Change from baseline emotional regulation
时间窗: Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up
Difficulties in Emotion Regulation Scale
Change from baseline attention
时间窗: Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up
Attention Network Task
Change from baseline self-awareness
时间窗: Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up
Mindful Attention Awareness Scale
Change from baseline inflammatory gene expression
时间窗: Before the intervention and on the final day of the intervention
次要结局
- Change from baseline risk-taking(Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up)
- Change from baseline empathy(Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up)
- Change from baseline stress(Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up)
- Change from baseline social learning(Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up)
- Change from baseline affective states(Before the intervention, up to 2 weeks after the intervention and at 10-18 week follow-up)
研究者
Ivana Buric
MA, Doctoral candidate
Coventry University