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临床试验/NCT06145230
NCT06145230招募中不适用

A Cross-sectional Survey of Symptomatic Characteristics, Family History and Pathologic Features of Colorectal Cancer Patients in Different Age Groups

Wang Guiyu1 个研究点 分布在 1 个国家目标入组 430 人开始时间: 2023年12月12日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
430
试验地点
1
主要终点
Characteristics of clinical symptoms

研究概览

简要总结

This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

详细描述

Colorectal cancer is one of the common and highly prevalent malignant tumors of the gastrointestinal system. Previous studies have found that there may be some differences in disease characteristics and prognosis of colorectal cancer patients at different ages, such as patients with early-onset colorectal cancer (age <50 years) tend to have a worse prognosis than patients with late-onset colorectal cancer (age ≥50 years). However, existing studies on the characteristics of colorectal cancer patients at different ages are not well studied to answer the differences between these patients and develop targeted diagnostic and treatment strategies. Cross-sectional survey research, which uses survey research to collect data on a characteristic group over a certain period of time and statistically analyzes the data to obtain the characteristics of a certain disease or a certain treatment strategy, is a more mature approach that is particularly suitable for the questions that need to be answered in this study. Investigators found that no similar studies have been registered and conducted by searching the official websites of the China Clinical Research Registry and Clinical Trial, and there is a lack of research data on the Chinese population. Therefore, investigators believe there is an urgent need for a cross-sectional survey to study the symptomatic characteristics, family history, and pathologic features of colorectal cancer patients. This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological characteristics of patients of different ages, so as to provide help and basis for more accurate and earlier prevention and treatment of colorectal cancer.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Adults aged 18 years and older with a pathologic diagnosis of colorectal cancer;
  • Undergoing surgical treatment of the primary lesion;
  • Voluntary participation of patients.

排除标准

  • Do not agree to participate in the survey or withdraw informed consent
  • Patients did not receive surgical treatment or did not undergo pathologic examination

结局指标

主要结局

Characteristics of clinical symptoms

时间窗: 2023.12-2024.10

Comparison of the characteristics of clinical symptoms in patients of different ages;

Family history

时间窗: 2023.12-2024.10

Comparison of the probability of having a family history in patients of different age stages;

Pathological characteristics

时间窗: 2023.12-2024.10

Comparison of pathological characteristics of patients at different age stages;

次要结局

  • Risk factors(2024.09-2024.10)

研究者

发起方
Wang Guiyu
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Wang Guiyu

Director of the Department of Colorectal Cancer Surgery

The Second Affiliated Hospital of Harbin Medical University

研究点 (1)

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