NCT03505541CompletedNot Applicable
Effect of Adiponectin and TNFa on Uterine Contractility in GDM and Obese Pregnant Patients
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Minnesota
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- Effect on force of contractility
Study Overview
Brief Summary
Investigate the effect of two adipokines which are adiponectin and TNFa on the force of myometrial contractility in diabetic, non-obese pregnant women and obese, non-diabetic term pregnant women at the time of scheduled cesarean delivery
Study Design
- Study Type
- Observational
- Observational Model
- Cohort
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 55 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Pregnant patients scheduled for a CS at 37-41 weeks of gestation at M Health Birth Place
- •Participants age ≥
- •Full informed consent able to be provided by the participant.
Exclusion Criteria
- •Patients undergoing general anesthesia for their CS.
- •Pre-gestational DM, and DM diagnosed <24 weeks gestation.
- •Patients unable to consent for themselves
- •Multiple gestation
Outcomes
Primary Outcomes
Effect on force of contractility
Time Frame: 24 hours
Determine the effect of adiponectin and TNFa on the force of myometrial contractility in diabetic, non-obese pregnant women and obese, non-diabetic term pregnant women at the time of scheduled cesarean delivery
Secondary Outcomes
- Progesterone effect in control group(24 hours)
- Force of contractility between study groups(24 hours)
Investigators
Study Sites (1)
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