IRCT201104224365N8已完成2 期
Comparison of cardioplegic solutions which contain lidocaine or procaine hydrochloride in cognitive function after CABG surgery
Vice chancellor for research of Mazandaran University of Medical Sciences0 个研究点目标入组 110 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 110
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 20 years 至 70 years（—）
- 性别
- All
入选标准
- •Informed written consent; Elective CABG surgery; Age between 20 and 70 years; Use of the cardiopulmonary pump during surgery.
- •Exclusion criteria: History of symptomatic cerebrovascular disease; Alcohol use (> 50 cc /day); History of psychiatric illness (any clinical diagnosis requiring therapy); History of drug abuse (any illicit drug abuse in the past 3 months); Hepatic insufficiency (liver function tests > 1.5 times of the normal upper limit); Sever pulmonary insufficiency (requiring home oxygen therapy); Renal failure (baseline serum creatinine > 2mg/dl); Lack of cooperation in response to cognitive test; together with other cardiac surgery (valvular surgery); History of previous cardiac surgery; Ejection fraction < 35%; history of sensitivity to lidocaine or procaine hydrochloride.
排除标准
- 未提供
研究者
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