Comparison of Leucine-Rich Alpha-2-Glycoprotein-1 (LRG-1) blood Levels Between Patients With and Without Appendicitis

Not Applicable

Active, not recruiting

Conditions: Acute appendicitis, unspecified
K35.9

Registration Number: RBR-9dxqbk

Lead Sponsor: Hospital de Clínicas de Porto Alegre

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruitment completed

Sex: Not specified

Target Recruitment: Not specified

Inclusion Criteria

Recent abdominal pain (less than 30 days) with at least one more of the other criteria; pain in the right iliac region; pain migrating; nausea or vomiting before vomiting; psoas sign; fever; rebound tenderness (Blumberg sign); abdominal rigidity; no previous similar pain; pain to digital rectal examination; anorexia.

Exclusion Criteria

Refusal to participate in the study; have already undergone appendectomy.

Study & Design

Study Type: Observational

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Presentation of the expected outcome:<br>Quantitatively assess plasma LRG1 levels.<br>Presentation of the method used to verify the expected outcome: ELISA.<br><br>Presentation of the parameters (ng / ml) used to verify whether the outcome actually occurred:<br><br>We will quantify the plasma LRG1 concentration (in ng / ml) in patients with and without the diagnosis of acute appendicitis.<br><br>We expect to see a difference of 53 ng / ml in the group without appendicitis to 95 ng / ml for the group with appendicitis, having a 95% power and an alpha error of 1%

Secondary Outcome Measures