Observational Study of Exposure to Environmental Toxicants Among Firefighters
Recruiting
- Conditions
- Healthy
- Interventions
- Other: Sample collection
- Registration Number
- NCT05643014
- Lead Sponsor
- Masonic Cancer Center, University of Minnesota
- Brief Summary
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Firefighter (career or volunteer)
- Over 18 years of age
- Able to provide written voluntary consent
Exclusion Criteria
- Unwilling to provide a pre and post-exposure urine sample
- Current cancer diagnosis
- Tobacco use within the last 1 year (verified by urinary TNEs)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Firefighters over 18 years old Sample collection This is a within subject, observational study of firefighters. This study will involve three sample collections including buccal cells and urine samples; one collection pre and two collections post-structural fire exposure.
- Primary Outcome Measures
Name Time Method Studying biomarker levels in firefighters pre and post fire call. 48 months The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Masonic Cancer Center
🇺🇸Minneapolis, Minnesota, United States