The Diagnostic Yield of Narrow Band Imaging Videobronchoscopy in Lung Cancer
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 101
- 试验地点
- 1
- 主要终点
- accuracy of NBI videobronchoscopic biopsy
研究概览
简要总结
Narrow band imaging (NBI) videobronchoscopy is an optical technique in which filtered light enhances superficial neoplasm based on their neoangiogenic pattern. The objectives of this study investigate its better diagnostic yield in the assessment of lung cancer than conventional flexible bronchoscopy.
详细描述
Inspection with high resolution endoscopy was followed by NBI. Detected lesions were biopsied. applied the system of shibuya et al. to analyze and classify vascular patterns by NBI into four categories (spiral and screw pattern, dotted pattern, tortuous pattern, avascular pattern) compared with the known diagnostic yield of conventional white light bronchoscopy, An equivalent or superior result will also significantly impact on patient care This technology could aid not only early-stage lung cancer diagnosis but also more accurate local staging of lung cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •endobronchial lesion on chest CT
排除标准
- •Age < 18 years old
- •Inability to consent for the study
- •Inability to tolerate bronchoscopy
- •Active pulmonary infection (bronchitis, pneumonia)
- •ST elevation or depression on ECG
- •Prothrombin time prolongation(<70%)
- •platelet <10,000
结局指标
主要结局
accuracy of NBI videobronchoscopic biopsy
时间窗: 10-11 months
Define and compare the sensitivity, specificity, positive predictive value, negative predictive value, likelihood ratio and accuriacies for the diagnostic techniques for lung cancer.
次要结局
- early cancer lesion detection rate using Shibuya descriptors(10-11 months)