Outcomes in Hospitalized Older Patients With COVID-19

Completed

• Conditions: Sars-CoV2; Coronavirus Infection; Elderly Infection; Old Age; Debility

• Registration Number: NCT04385212
• Lead Sponsor: University Hospital, Geneva

Brief Summary

In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly understood in older patients and is certainly different from the general population. This project is designed to better understand and to determine clinical, biological and radiological markers of poor adverse outcomes in hospitalized older patients diagnosed with COVID-19.

Detailed Description

Not available

Study Timeline

• Study Start: 2020-03-13
• Primary Completion: 2020-04-14
• Study Completion: 2020-04-14
• Study First Submitted: 2020-04-29
• Status Verified: 2020-05
• Study First Submitted QC: 2020-05-08
• Last Update Submitted: 2020-05-08
• Study First Posted: 2020-05-12
• Last Update Posted: 2020-05-12

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 230

Inclusion Criteria

• Diagnosis of COVID-19, defined by a positive polymerase chain reaction (PCR) test for SARS-CoV-2 detection, obtained by a nasopharyngeal swab or sputum sample.
• Or patients with negative virus detection in the PCR test, but with a high clinical suspicion will also be considered with COVID-19.

Exclusion Criteria

• Presence of document indicating a refusal to participate in a research study.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To evaluate the relative contributions of comorbidities on intra-hospitalized death	1 month	We measure functional score of comorbidities

Secondary Outcome Measures

Name	Time	Method
To evaluate the relative contributions of functional characteristics on intra-hospitalized death	1 month	We measure Functional Independence Measure scale
To explore specific clinical profiles that may influence COVID-19 disease outcomes in the elderly based on geriatrics syndromes	1 month	We describe the role fo geriatric syndrome such as delirium, falls

Trial Locations

Locations (1)

Department of Rehabilitation and Geriatrics; 🇨🇭 Geneva, Switzerland