The safety and efficacy of baclofen for alcohol dependence: a double-blind randomised placebo-controlled trial

Sydney South West Area Health Service0 sites42 target enrollmentMarch 15, 2006

Overview

No summary available.

Registry

who.int

Start Date

March 15, 2006

End Date

TBD

Last Updated

6 years ago

Study Type

Interventional

Sex

All

Sponsor

•DMS\-IV criteria for alcohol dependence; Meets criteria for current heavy drinking; Can provide informed written consent; 3\-days abstinence prior to treatment; Desires abstinence or to greatly reduce alcohol consumption; Has stable residence and can provide collateral contact details.

•Clinically significant medical disease that might interfere with the evaluation of the study medication or present a safety concern; Clinically significant psychiatric illness or substance use disorder other than alcohol or nicotine dependence or cannabis abuse; Concurrent use of any psyhotropic medication (except subjects on stable antidepressant doses \> 2 months); Concurrent use of anticonvulsants, insulin or oral hypoglycemics, History of complicated alcohol withdrawal; Extremely abnormal LFTs; Women who are pregnant or breadfeeding; Requiring inpatient or more intense outpatient treatment for alcohol dependence; Court\-mandated participation in alcohol treatment or impending incarceration.