Assessment of lipid profile changes in chronic kidney disease patients : Cross-sectional study

·       Cardiovascular disease (CVD) is a major cause of mortality in patients with mild to moderate chronic kidney disease (CKD) and end stage renal disease (ESRD.

·       Hyperlipidemia, one of the important risk factors of atherosclerosis, is an abnormality commonly encountered in patients with chronic kidney disease.

·       Patients with chronic kidney disease have other risk factor includes hypertension, diabetes mellitus, smoking, and obesity

·       Previous Studies demonstrates that CRF is commonly accompanied by lipid abnormality in the form of Hypertriglyceridemia

·       The present study is undertaken to explore the altered lipid abnormalities in CKD from stage I to stage V classified as per National Kidney Foundation Kidney Disease Outcomes Quality Initiative (NKFK/DOQI) guidelines, which plays a vital role in development of atherosclerotic cardiovascular disease.

·       An attempt is made to correlate the clinical features with biochemical profile to classify the etiology and outcome on the hospitalized patients.

a. Eligibility Criteria:

Inclusion:

All patients of Chronic Kidney Disease with  age  18  years  or  above,  who  give consent for study

Exclusion Criteria

Patients who do not fill the above criteria.

Patients with renal transplant.

Patients with nephrotic syndrome.

Pregnant Female patients.

Immunocompromised patients.

Provisional Conclusion :

Decrease in hdl level and increase in ldl,vldl,tg,tc in ckd patients on hemodialysis as compared to ckd patients on conservative management