Will Lactobacillus Increase Cure Rate After Treatment of Bacterial Vaginosis and Chronic Vulvovaginal Candida

Completed

• Conditions: Bacterial Vaginosis

• Registration Number: NCT02295579
• Lead Sponsor: Skaraborg Hospital

Brief Summary

From the earlier studies the investigators have treated women with bacterial vaginosis and cronic vulvovaginal candida. The investigators have then treated them with laktobacilli 10 days for 2 month. The investigators will continue to follow them and investigate if treatment with lactobacilli every week for 6 month will increase cure rate.

Detailed Description

Clinical diagnosis of bacterial vaginosis using air dried smears combined with Hay/Ison classification. Test of cure every month or every menstrual cycle using self taken smears. The cure will be if the woman are in group 1 according to Hay/Ison classification. This will also allow us to use molecular diagnosis of BV to test cure and compare this with hay/Ison.

Test of cure for candida patiens are no visibel candida on wet smear and free of symtoms of candida.

Study Timeline

• Study Start: 2014-06
• Study First Submitted: 2014-10-30
• Study First Submitted QC: 2014-11-19
• Study First Posted: 2014-11-20
• Primary Completion: 2015-06
• Study Completion: 2015-11
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-12
• Last Update Posted: 2019-08-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 50

Inclusion Criteria

• Diagnosis of bacterial vaginosis according to Hay/Ison or with candida diagnosed with wet smear.

Exclusion Criteria

• Women with chlamydia infection, Pregnancy, Herpes

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
cure rate	6 month

Secondary Outcome Measures

Name	Time	Method
colonization of lactobacilli	6 month

Trial Locations

Locations (2)

Department of Ob/Gyn, Skaraborgshospital Skövde; 🇸🇪 Skövde, Sweden

Kvinnokliniken; 🇸🇪 Skövde, Sweden