An exploratory investigation of the biomarker for senescence and arteriosclerosis in renal transplant donors and recipients.
Not Applicable
Recruiting
- Conditions
- Recipients and donors in living-kidney transplantation
- Registration Number
- JPRN-UMIN000004905
- Lead Sponsor
- Kagawa University, Faculty of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
Not provided
Exclusion Criteria
1)Kidney transplant from cadaver donors or brain-dead donors. 2)Patients who are under 16 years-old 3)Patients without agreement 4)Patients inadequate for the study
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1)AGT (urine and serum),soluble (pro) renin receptor (urine and serum) and plasma AMDA: 0,12,36,60 months 2)Senescence-associated beta galactosidase and arteriosclerosis in donated kidney or allograft: 0,12,36,60 months
- Secondary Outcome Measures
Name Time Method 1)Cr and eGFR in donors and recipients: 0,6,12,24,36,48,60 months 2)CAVI and central BP: 0,12,36,60 months 3)urinary albumin, proteinuria and urinary occult blood: 0,6,12,24,36,48,60 months 4)patient survival rates, allograft survival rates and cardiovascular events: 0-60months 5)BP: 0,6,12,24,36,48,60 months