Total Intravenous Anesthesia in Percutaneous Transhepatic Cholangiography

• Conditions: Percutaneous Transhepatic Cholangiography
• Interventions: Procedure: Percutaneous transhepatic cholangiography

• Registration Number: NCT03103672
• Lead Sponsor: Inonu University

Brief Summary

Percutaneous transhepatic cholangiography is a disturbing procedure for patients.

TIVA with short-acting anesthetics such as propofol and remifentanil is characterized by hemodynamic stability and better compilation profile The purpose of this study; To compare total intravenous anesthesia with inhalation anesthesia in patients undergoing percutaneous transhepatic cholangiography under general anesthesia.

Detailed Description

Percutaneous transhepatic cholangiography is a disturbing procedure for patients. Especially pain at the time of dilation can be a serious problem. These situations may be required local anesthetics, intravenous narcotics and sedatives or general anesthesia (1).

TIVA with short-acting anesthetics such as propofol and remifentanil is characterized by hemodynamic stability and better compilation profile (2).

The purpose of this study; To compare total intravenous anesthesia with inhalation anesthesia in patients undergoing percutaneous transhepatic cholangiography under general anesthesia and Determine their advantages and disadvantages.

1. Michael J. Lee, Peter R. Mueller, Sanjay Saini, Peter F. Hahn, Stewen L. Dawson. Percutaneous Dilatation of Benign Biliary Strictures: Single-Season Therapy with General Anesthesia. AJR: 157, December 1991: 1263-1266

2. Xiaoqian Deng, Tao Zhu. Clinical comparison of propofol-remifentanil TCI with sevoflurane induction / maintenance anesthesia in laparoscopic cholecystectomy. Pak J Med Sci 2014 Vol. 30 No. 5: 1017-1021

Study Timeline

• Study Start: 2017-01-02
• Study First Submitted: 2017-03-31
• Study First Submitted QC: 2017-04-05
• Study First Posted: 2017-04-06
• Status Verified: 2022-04
• Last Update Submitted: 2022-04-04
• Last Update Posted: 2022-04-05
• Primary Completion: 2023-11-01
• Study Completion: 2023-12-30

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Adult patients undergoing percutaneous transhepatic cholangiography with general anesthesia

Exclusion Criteria

• Essential data were missing
• Patient participating in other research projects
• Drug allergy
• Anesthetic complication story

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Groupe I	Percutaneous transhepatic cholangiography	Patients who will receive inhalation anesthesia
Groupe 2	Percutaneous transhepatic cholangiography	Patients who will receive total intravenous anesthesia

Primary Outcome Measures

Name	Time	Method
Recovery time from anesthesia	up to postoperative 1 hours	Time for Modified Aldrete Score 9 and over

Secondary Outcome Measures

Name	Time	Method
Heart rate	up to postoperative 1 hours	Every 5 minutes during the process
Mean blood pressure	up to postoperative 1 hours	Every 5 minutes during the process