Brain Activation Pattern in Stroke Patients While Performing Gesture Components of A Clinical Prognostic Tool: A Cross-Sectional Analytical Study.
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- 1. Region of interest (ROI) accounts for global signal variations
研究概览
简要总结
The study, Brain Activation Pattern in Stroke Patients While Performing Gesture Components of a Clinical Prognostic Tool: A Cross-Sectional Analytical Study, aims to explore the brain activation pattern in stroke patients while performing gesture components of a clinical prognostic tool.Selected Participants: Subjects diagnosed with stroke along with age and gender-matched controls. In this study, informed consent will be obtained from the participants willing to participate, participant demographic data will be collected, and routine clinical evaluation will be done. Then Cognitive screening will be done using the Montreal Cognitive Assessment Scale, the Wolf Motor Function Tool (WMFT), and the Bedside Upper Limb Functional Evaluation Tool (BUFET) will be used to test upper limb motor function. Participants will be instructed on how to perform the gesture components of the BUFET. A structural MRI will be taken while subjects are positioned, and their heads will be held in place to limit movement. The individual will do the gesture components of BUFET in an fMRI scanner to find out which part of the brain are involved in movement actions
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 65.00 Year(s)(—)
- 性别
- All
入选标准
- •Adults aged 18 to 65 years with primary ischemic supratentorial stroke in the middle cerebral artery territory acute or sub-acute phase medically stable after 72 hours Brunnstrom stage of hand recovery between 3 to 5 Age and gender matched controls.
排除标准
- 未提供
结局指标
主要结局
1. Region of interest (ROI) accounts for global signal variations
时间窗: Baseline
2. BOLD signal changes per ROI represented by the mean beta value during each task
时间窗: Baseline
3. Laterality Index (LI):
时间窗: Baseline
Quantifies hemispheric dominance in activation.
时间窗: Baseline
次要结局
- Region of interest (ROI) accounts for global signal variations(2. BOLD signal changes per ROI represented by the mean beta value during each task)
研究者
Muskhan
Kasturba Medical College ,Mangalore
