Effect of transdermal estradiol on endometrial preparation in frozen-thawed embryo transfer

Phase 4

Completed

• Conditions: Women undergoing IVF; Pregnancy and Childbirth

• Registration Number: ISRCTN15301227
• Lead Sponsor: Hung Vuong Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-02
• Study Completion: 2022-03-31
• Last Update Posted: 2022-08-29

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 380

Inclusion Criteria

1. Women aged 18-45
2. No history of uterine intervention: suction or endoscopy
3. Has FET indication
4. Has at least one excellent/good frozen embryo before thawing
5. No pathological background: diabetes, high prolactin level, thyroid disorders, adrenal gland disorders.
6. Agree with FET indication
7. Volunteer to the study and has full contact information

Exclusion Criteria

1. BMI > 30
2. Egg or embryo donor/receiver
3. Estradiol contraindication
4. Estradiol usage > 27 days
5. Not qualified for FET
6. Abnormal uterine, fallopian tube related to implantation
7. Endocrine disorders (kidney, liver or cardiac disease)
8. Patient does not agree to participate in the study
9. Patient does not adhere to the study
10. Does not follow drug prescription:
10.1. Patient forgot to consume drug for more than 2 consecutive or non-consecutive days
10.2. Patient stops using drug due to personal reasons
11. Late follow-up examination
12. Cannot read or write Vietnamese

Study & Design

• Study Type: Interventional
• Study Design: Not specified