Effects of umbilical cord derived mesenchymal stem cells injection in the treatment of children with cerebral palsy

Phase 2

• Conditions: Spastic Cerebral Palsy.; Spastic quadriplegic cerebral palsy; G80.0

• Registration Number: IRCT20110628006907N18
• Lead Sponsor: ROYAN stem cell technology Co

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 3 April 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Spastic cerebral palsy (Dip, Quadri, Hemiparetic ) Ages between 2 - 14 years Gross motor function classification (GMFC) 2 -4 No seizure disorder or with controlled seizure Acquired brain MRI finding compatible with CP Informed consent of parents

Exclusion Criteria

Normal brain MRI Progressive neurological diseases Congenital brain cortical malformations TORCH infections( Toxoplasmosis, Others, Rubella Cytomegalovirus Hepatitis C ) Other types of cerebral palsy (athetoid , atonic , ataxic , mixed ) Acute infections (Human Immunodeficiency Virus , Hepatitis C Virus ) Hemorrhagic diathesis Severe anemia ( Hemoglobin less than 8 ) Ventilator dependent pulmonary diseases Severe renal dysfunction Severe liver dysfunction

Study & Design

• Study Type: interventional
• Study Design: Not specified