Efficacy of Intermediate and High Intensity Regimens in Patients With Relapsed Acute Lymphoblastic Leukemia
- Conditions
- Acute Lymphoblastic Leukemia
- Registration Number
- NCT04699162
- Lead Sponsor
- Christian Omar Ramos-Peñafiel, MD, PhD
- Brief Summary
The aim of this study is to describe the survival and relapses of patients with diagnosis of acute lymphoblastic leukemia at two tertiary level hospitals in the metropolitan area of the valley of Mexico
- Detailed Description
Retrospective, observational study in patients with diagnosis of acute lymphoblastic leukemia, according to the criteria of the World Health Organization, from July, 2016, to October, 2020. The patients were cared for in the hematology department of the Hospital General de Mexico and in the hematology department of the Hospital Regional de Alta Especialidad Ixtapaluca. Relapse was considered in those cases with more than 5% of blasts in bone marrow and as relapse to the central nervous system with the presence of blasts in cerebrospinal fluid.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 56
- Patients with diagnosis of acute lymphoblastic leukemia according to the criteria of the World Health Organization.
- Age less than 15 years
- Age over 60 years
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Overall survival 4-years Progression free survival 4-years Number of relapses 4-years Cases with more than 5 percent of blasts in bone marrow and as relapse to the central nervous system with the presence of blasts in cerebrospinal fluid
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Hospital General de México "Dr. Eduardo Liceaga"
🇲🇽Mexico City, Mexico
Hospital Regional de Alta Especialidad de Ixtapaluca
🇲🇽Ixtapaluca, State Of Mexico, Mexico