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Clinical Trials/NCT04867122
NCT04867122
Completed
Not Applicable

Problem-Solving Therapy for Cancer Caregivers: A Randomized Clinical Trial in Outpatient Palliative Care

Washington University School of Medicine4 sites in 1 country532 target enrollmentJanuary 24, 2022

Overview

Phase
Not Applicable
Intervention
Attention-matched Control
Conditions
Depression, Anxiety
Sponsor
Washington University School of Medicine
Enrollment
532
Locations
4
Primary Endpoint
Change in anxiety as measured by the PROMIS Short Form v1.0 - Anxiety 8a
Status
Completed
Last Updated
3 months ago

Overview

Brief Summary

This study is a randomized clinical trial of a problem-solving therapy intervention for family caregivers of individuals with cancer receiving outpatient palliative care.

Detailed Description

This study is a randomized clinical trial of a problem-solving therapy intervention for family caregivers of individuals with cancer receiving outpatient palliative care. Study participants will be randomized to receive either a three-session problem-solving therapy intervention in addition to usual care or three sessions of attention-matched control in addition to usual care.

Registry
clinicaltrials.gov
Start Date
January 24, 2022
End Date
December 1, 2025
Last Updated
3 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • for Family Caregivers (FCGs)
  • Must be 18 years of age or older
  • Must serve as the unpaid family caregiver of a patient with cancer receiving outpatient palliative care from one of the participating clinical sites. As is common in caregiving research, we will define "family caregiver" as anyone substantially involved in a patient's care on an unpaid basis; a legal or biological relationship will not be required
  • Must consent to participate
  • Inclusion Criteria for Non-Family Caregiver Stakeholders
  • Must be 18 years of age or older
  • Must be employed by or affiliated with the healthcare system housing one of the participating clinical sites.
  • Must consent to participate.

Exclusion Criteria

  • for Family Caregivers (FCGs)
  • Younger than 18 years of age
  • Paid caregiver
  • Exclusion Criteria for Non-Family Caregiver Stakeholders
  • Younger than 18 years of age
  • Not employed by or affiliated with the healthcare system housing one of the participating clinical sites.

Arms & Interventions

Attention Control

Family caregivers in the attention control study arm will receive three sessions of attention-matched control in addition to the services and support provided as part of usual outpatient palliative care. Attention-matched control will consist of three "friendly visits" with a trained research staff person.

Intervention: Attention-matched Control

Problem Solving Therapy Intervention

Family caregivers in the intervention study arm will participate in three problem-solving therapy sessions with a trained interventionist in addition to receiving the services and support provided as part of usual outpatient palliative care.

Intervention: Problem-Solving Therapy

In-Depth Interviews for non-FCG Stakeholders

Each year of the project, the investigators will recruit 6 key stakeholders to participate in individual interviews focused on potential barriers and facilitators to adoption of the PST intervention into clinical practice for a total of 30 unique stakeholders who will be interviewed over the duration of this 5-year study.

Intervention: In-depth interviews

Outcomes

Primary Outcomes

Change in anxiety as measured by the PROMIS Short Form v1.0 - Anxiety 8a

Time Frame: At the time of enrollment, Week 4, and 30-day follow-up

Family caregivers indicate the frequency with which they experience eight different symptoms of anxiety (8 items); higher scores reflect higher anxiety severity.

Change in symptoms of depression as measured by the PROMIS Short Form v1.0 - Depression 8a

Time Frame: At the time of enrollment, Week 4, and 30-day follow-up

Family caregivers indicate the frequency with which they experience eight different symptoms of depression (8 items); higher scores reflect higher depression severity

Secondary Outcomes

  • Change in positive aspects of caregiving as measured by Positive Aspects of Caregiving Scale - Short Form (S-PAC; 7 items)(At the time of enrollment, Week 4, and 30-day follow-up)

Study Sites (4)

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