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Clinical Trials/NCT04552652
NCT04552652
Terminated
N/A

Effect of Home-based High-Intensity Interval Training Using TeleRehabilitation Among Coronary Heart Disease Patients

Brno University Hospital1 site in 1 country76 target enrollmentJune 1, 2021

Overview

Phase
N/A
Intervention
Not specified
Conditions
Coronary Artery Disease
Sponsor
Brno University Hospital
Enrollment
76
Locations
1
Primary Endpoint
Cardiorepisratory fitness (CRF)
Status
Terminated
Last Updated
2 years ago

Overview

Brief Summary

Telerehabilitation has the potential to become an alternative attitude to outpatient cardiac rehabilitation. The aim of our study is to research the method of high-intensity interval training in the home environment using telerehabilitation. Investigators assume that the high-intensity interval training form of telerehabilitation, using a heart rate monitor as a tool for backing up training data, can improve physical fitness and lead to higher peak oxygen uptake as the traditional moderate-intensity continuous training. The study is designed as a monocentral randomized controlled trial at University Hospital Brno in the Czech Republic.

After the coronary event, eligible patients will be randomly (in 1:1 ratio) separated into two groups: the experimental high-intensity interval training group and the moderate-intensity continuous control group. Both groups undergo a 12-week telerehabilitation training program with a 52-week follow-up period. The primary outcome observed will be the effect of intervention expressed by changes in peak oxygen uptake values.

Detailed Description

The study relates to the previous study project CR-GPS, in which investigators proved the feasibility of cardiac telerehabilitation. The results showed that aerobic capacity and quality of life improved similarly in telerehabilitation and outpatient group of participating patients. During the research, investigators used the moderate-intensity continuous method. The present research focuses on high-intensity interval training, which presents comparable or even better results in cardiorespiratory condition effects and requires less time than a continuous method in patients with low or medium cardiovascular risk.

Registry
clinicaltrials.gov
Start Date
June 1, 2021
End Date
July 25, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Brno University Hospital
Responsible Party
Principal Investigator
Principal Investigator

Ladislav Batalik

Principal Investigator

Brno University Hospital

Eligibility Criteria

Inclusion Criteria

  • Participants with coronary artery disease (in last two months)
  • with low or medium cardiovascular risk
  • with heart revascularization
  • with recommended pharmacotherapy
  • with clinically stable state
  • with the ability to perform a cardiopulmonary exercise test
  • with the ability to understand and write in the Czech language
  • with an internet connection at home
  • literacy with information and communication technology

Exclusion Criteria

  • Participants who were hospitalized with heart disease in the previous six weeks
  • with psychological severe or cognitive disorders
  • with contraindications for cardiopulmonary exercise testing
  • with severe training limitations besides coronary artery disease
  • with a planned intervention or operation
  • participants who are enrolled in or participate in an outpatient form of cardiac rehabilitation
  • participants who plan to be or are included in other studies

Outcomes

Primary Outcomes

Cardiorepisratory fitness (CRF)

Time Frame: Change from baseline to 12 weeks and 52weeks

Peak oxygen uptake (VO2peak) during cardiopulmonary exercise test

Secondary Outcomes

  • Training adherence (Number of compliant participants, Average exercise time, Overall completition rate)(12 weeks)
  • Anxiety (General anxiety disorder, 7-item scale)(Change from baseline to 12 weeks and 52weeks)
  • Incidence of treatment-emergent adverse events assessed by 5 grade scale(Data will be recorded continuously from the intervention's baseline for 12 weeks and then for 52 weeks.)
  • Health-related quality of life (SF-36 Form)(Change from baseline to 12 weeks and 52weeks)
  • Hospital Anxiety and Depression scale (HADS)(Change from baseline to 12 weeks and 52weeks)
  • Body composition (BIA)(Change from baseline to 12 weeks and 52weeks)
  • Satisfaction - self-completed questionnaire(12 weeks and 52weeks)

Study Sites (1)

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