跳至主要内容
临床试验/ISRCTN14165977
ISRCTN14165977进行中(未招募)未知

Relationship of antifungal exposure to emergence of Candida resistance in Intensive Care patients: a multi-site cohort study

St George’s University Hospitals NHS Foundation Trust0 个研究点目标入组 400 人开始时间: 2021年11月29日最近更新:

试验速览

阶段
未知
状态
进行中(未招募)
发起方
入组人数
400

研究概览

简要总结

暂无简介。

研究设计

研究类型
Observational

入排标准

性别
All

入选标准

  • 1. Age =18 years
  • 2. Currently receiving intravenous antibiotics
  • 3. One or more of the following Candida risk factors:
  • 3.1. Abdominal surgery in the last 4 weeks
  • 3.2. Upper gastrointestinal/mediastinal perforation or surgery in the last 4 weeks
  • 3.3. Liver failure
  • 3.4. Haematological malignancy
  • 3.5. Previous bone marrow or solid organ transplant
  • 3.6. Neutropenia (neutrophils < 0.5*10e9/l)
  • 3.7. Receipt of an immunosuppressive drug (including corticosteroids, chemotherapy, immune-modulators)
  • 3.8. Total parenteral nutrition (TPN)
  • 3.9. Renal replacement therapy
  • 3.10. Extracorporeal membrane oxygenation (ECMO)
  • 4. Suspected invasive candidiasis (added 25/08/2023)

排除标准

  • Expected ICU length of stay <48 h

研究者

发起方
St George’s University Hospitals NHS Foundation Trust

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