Effectiveness of Using Nano-Silver Fluoride Varnish Versus Sodium Fluoride Varnish in Management of Cervical Dentin Hypersensitivity in Adult Patients: A Randomized Clinical Trial.
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 42
- Primary Endpoint
- change in dentin Hypersensitivity
Study Overview
Brief Summary
2 different varnishes will be used to test their effectiveness in controlling teeth hypersensitivity in adult patient.
Detailed Description
In-vivo part:
Each varnish will be applied separately on different teeth according to the manufacturer's instructions and the VAS will be measured according to a specific timeline: T0 (baseline, before application of varnish), T1 (1 week after application), T2 (4 weeks after application) and T3 (4 weeks after application).
In-situ part:
Dentin specimen will be prepared from extracted teeth from the orthodontic department in our college, sterilized and prepared.
it will be bonded to an orthodontic wire and bonded to upper first molar. Dentinal occlusion will be measured using scanning electron microscope following the same timeline.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Triple (Participant, Care Provider, Outcomes Assessor)
Eligibility Criteria
- Ages
- 25 Years to 50 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Patients consulting in one of the Qasr Einy, faculty of dentistry outpatient clinics.
- •Males or females.
- •Patient's age range 25-50 years.
- •Patients complaining of hypersensitive areas on facial surfaces of the teeth (incisors, cuspids, bi-cuspids, and first molars with exposed cervical dentine) with teeth scoring Bpain (VAS score: greater than or equal to 3) during application of stimulus (airblast and tactile sensitivity test).
- •Tooth with exposed root surface, complaining from hypersensitivity (VAS score; greater than or equal to 3).
- •Patients accept the 2-months follow-up period.
- •Provide informed consent.
Exclusion Criteria
- •• Patients participating in another dental study that may alter the results of this study.
- •A medical condition that could hinder the accuracy of pain reporting (e.g., pain disorders).
- •Any chronic medical condition that requires the regular use of anti-inflammatory pain medications.
- •Patients used or applied a desensitizing varnish within the last four weeks.
- •Patients with dental problems; chipped teeth, defective restorations, fractured Un-displaced cuspids or deep dental caries.
- •Lack of patient's approval and compliance.
Arms & Interventions
Citrine 5% Sodium Fluoride
It was developed to prolong the contact between the tooth surface and fluoride to increase the resistance against caries attack and manage tooth hypersensitivity; the active ingredient of fluoride varnish is mostly 5% sodium fluoride.
Intervention: Citrine 5 % sodium fluoride (Behavioral)
concocuted Nano-silver fluoride
Nano-silver fluoride (NSF) is a laboratory synthesized solution
Intervention: concocted nano-silver fluoride (Behavioral)
Outcomes
Primary Outcomes
change in dentin Hypersensitivity
Time Frame: 1 week, 4 weeks & 8 weeks
Visual Analogue Scale (VAS) will be used; 0 is no pain and 10 is severe pain. Pictures are added to the same, as well as colors to guide the patient during selection of pain severity.
Secondary Outcomes
- change in dentinal Tubule Occlusion(1 week, 4 weeks * 8 weeks)
Investigators
Nayera Hassanien Mohamed
Assistant Lecturer
Cairo University