Comparison of Weight Adjusted Dose versus Fixed Dose Ondansetron in Preventing Shivering Following Spinal Anesthesia for Cesarean Deliveries
Not Applicable
Completed
- Conditions
- shivering post spinal anesthesia in women undergoing cesarean sectionPregnancy and Childbirth
- Registration Number
- PACTR201611001473594
- Lead Sponsor
- AGA KHAN UNIVERSITY NAIROBI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 124
Inclusion Criteria
All ASA 1 and 2 healthy patients over 18 years scheduled for cesarean deliveries under spinal anesthesia.
Exclusion Criteria
Pre-operative use of ondansetron, tramadol, pethidine, clonidine. This drugs have been used in the prevention and treatment of shivering.
Allergy or intolerance to ondansetron.
Presence of shivering before drug administration.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie ondansetron's efficacy in preventing post-spinal shivering during cesarean deliveries?
How does weight-adjusted ondansetron compare to fixed-dose regimens in preventing post-spinal shivering in obstetric patients?
Are there specific biomarkers or patient characteristics that predict response to ondansetron in post-spinal shivering prevention?
What are the known adverse events associated with ondansetron use in pregnant women undergoing cesarean section?
What combination therapies with ondansetron show synergistic effects in managing post-spinal shivering during C-sections?