A Study of Two Different Light Conditions for Healthy Subjects Above 65 Years
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 29
- 主要终点
- Sleep length
研究概览
简要总结
to investigate the effect of two lightning conditions on sleep hypothesizing that sleep length is influenced by the color of light during daytime
详细描述
Lightning conditions seems to be important for the length and quality of sleep, as light have an influence on the production of the sleep hormone (melatonin) and the the circadian rhythm. Entrainment of the circadian rhythm to the surroundings is accomplished by light-sensitive retinal ganglion cells and these cells are sensitive to blue light.
Based on previous research, blue light early in the day and abscence of blue light during evening is important for the entrainment.
In this study, lightning conditions in the home of healthy subjects are set to either blue enriched or red enriched from 8 a.m to 1. p.m. The lightning condition is based on a randomization protocol in a cross-over study for 3 weeks in each condition, separated by a one week pause.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 65 Years 至 85 Years（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 65 to 85 years
排除标准
- •Conditions which will interfere by the primary endpoint as evaluated by the medical doctor
研究组 & 干预措施
red light
red light during the whole day
干预措施: blue light (Other)
Blue light
Blue light during early day
干预措施: blue light (Other)
结局指标
主要结局
Sleep length
时间窗: 1 week
The mean of sleep length during the last week of each light period
次要结局
- actigraphy(1 week)
研究者
Line Kessel
MD
Glostrup University Hospital, Copenhagen