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Clinical Trials/ISRCTN62326938
ISRCTN62326938
Completed
Phase 3

A multi­centre randomised controlled trial of pre­hospital blood product administration versus standard care for traumatic haemorrhage

niversity Hospitals Birmingham NHS Foundation Trust0 sites432 target enrollmentJuly 11, 2016
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ConditionsTraumatic haemorrhageInjury, Occupational Diseases, Poisoning

Overview

Phase
Phase 3
Intervention
Not specified
Conditions
Traumatic haemorrhage
Sponsor
niversity Hospitals Birmingham NHS Foundation Trust
Enrollment
432
Status
Completed
Last Updated
last year
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/29193548 protocol (added 06/03/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35271808/ (added 11/03/2022) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/38224557/ (added 02/09/2024)

Registry
who.int
Start Date
July 11, 2016
End Date
May 31, 2021
Last Updated
last year
Study Type
Interventional
Sex
All

Investigators

Sponsor
niversity Hospitals Birmingham NHS Foundation Trust

Eligibility Criteria

Inclusion Criteria

  • •1\. Traumatic injury
  • •2\. Pre\-Hospital Emergency Medical team attend
  • •3\. Hypotension (SBP \<90mmHg or absence of palpable radial pulse) believed to be due to traumatic haemorrhage

Exclusion Criteria

  • •1\. Children (known or apparently aged \<16 years)
  • •2\. Refusal of blood product administration; known Jehovah’s Witness
  • •3\. Pregnancy (known or apparent)
  • •4\. Isolated head injury

Outcomes

Primary Outcomes

Not specified

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