Nutraceutical Supplement in the Management of Hypertension

Phase 1

Completed

• Conditions: Hypertension
• Interventions: Dietary Supplement: Cardiopressin; Dietary Supplement: Placebo

• Registration Number: NCT02663479
• Lead Sponsor: Thorne HealthTech, Inc

Brief Summary

The purpose of this study is to evaluate the efficacy and safety of a proprietary nutraceutical supplement in capsule form over 4 months in treating blood pressure in a group of chronic hypertensive subjects that are not receiving any pharmaceutical anti-hypertensive agents or other nutraceutical supplements.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09
• Study First Submitted: 2016-01-18
• Study First Submitted QC: 2016-01-21
• Study First Posted: 2016-01-26
• Primary Completion: 2017-08
• Study Completion: 2017-10
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-12
• Last Update Posted: 2020-03-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cardiopressin	Cardiopressin	A 5 capsule proprietary blend of herbal extracts and nutrients
Placebo	Placebo	A 5 capsule placebo matched in color and size to the Experimental supplement

Primary Outcome Measures

Name	Time	Method
Blood Pressure	4 months	Reduction in systolic and diastolic blood pressure as measured by office readings and 24 hour ABM ( ambulatory blood pressure monitor)

Secondary Outcome Measures

Name	Time	Method
Endothelial Function	4 months	Measured via Endopat
Small arterial compliance	4 months	Measured via computerized arterial pulse wave analysis (CAPWA)
Large arterial compliance	4 months	Measured via computerized arterial pulse wave analysis (CAPWA)
Central arterial blood pressure	4 months	Measured via computerized arterial pulse wave analysis (CAPWA)

Trial Locations

Locations (1)

Hypertension Institute of Nashville, TN; 🇺🇸 Nashville, Tennessee, United States