Paramedic Randomized Trial of Noradrenaline Versus Adrenaline in the Initial Management of Patients with Cardiogenic Shock: The PANDA Trial
Phase 3
Recruiting
- Conditions
- Cardiogenic ShockCardiovascular - Coronary heart diseaseCardiovascular - Other cardiovascular diseases
- Registration Number
- ACTRN12621000805875
- Lead Sponsor
- Ambulance Victoria
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 1155
Inclusion Criteria
•Adult (aged 18 years or older)
•Evidence of shock with an indication to commence vasoactive infusion as per Ambulance Victoria Clinical Practice Guidelines and systolic blood pressure <=90mmHg despite adequate filling.
•Suspected cardiac aetiology.
Exclusion Criteria
•Suspected traumatic, anaphylactic or asthmatic aetiology of shock
•Heart rate < 50 beats per minute
•Transferred from another healthcare facility
•Cardiac arrest with greater than or equal to 30 minutes of cardiopulmonary resuscitation prior to return of spontaneous circulation.
•Patient dependent on others for activities of daily living
•Female who is known or suspected to be pregnancy
•Receiving vasoactive infusion prior to randomisation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method