Correlation Between Pupil Size and Ocular Signs in Pseudoexfoliation Syndrome (PEX): a Contralateral Eye Study.
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Pseudoexfoliation Syndrome
- Sponsor
- Assiut University
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- correlation between pupil size and severity of Pseudoexfoliation
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
To study possible correlation between the size of the pupil in both room light and after dilation between both eyes in bilateral pseudoexfoliation with Intraocular pressure, lens clarity and stability, Optic disc , Visual changes and glaucoma changes by optical coherence tomography
Detailed Description
For each patient. Full preoperative ophthalmological assessment will be done using slit lamp , size of the pupil in regular room light (usually around 2000 Lux) and post dilation with tropicamide 1%. baseline IOP measurement using Goldmann applanation tonometer, UCDVA (Uncorrected Distance Visual Acuity)and CDVA (Corrected Distance visual acuity), lens opacification or clarity, stability or subluxation. corneal endothelial cell count. Fundus examination using 90 D or 78D lenses, Humphrey visual field (24-2) analysis and optical coherence tomography on retinal nerve fiber layer (RNFL) and ganglion cell complex.(GCC)
Investigators
Mahmoud F. Rateb
Associate Professor
Assiut University
Eligibility Criteria
Inclusion Criteria
- •All patients with pseudoexfoliation syndrome
Exclusion Criteria
- •previous ocular surgery or ocular trauma affecting pupil. Any systemic or neurologic disease affecting pupil
Outcomes
Primary Outcomes
correlation between pupil size and severity of Pseudoexfoliation
Time Frame: 2-3 months
in each eye of the same patient we study correlation between pupil size with ntraocular pressure, lens status, corneal endothelial count and glaucomatous damage represented by (optic disc changes (cup to disc ratio) and OCT changes (RNFL and GCC)