Pilot-Study DCPT for PTSD in Adolescents and Young Adults

Not Applicable

Completed

• Conditions: PTSD
• Interventions: Behavioral: Developmentally adapted cognitive processing therapy

• Registration Number: NCT01870271
• Lead Sponsor: Goethe University

Brief Summary

The aim of this pilot study is to evaluate the developmentally adapted cognitive processing therapy (D-CPT)in adolescents suffering from childhood abuse(CA)or physical abuse (PA) related PTSD. D-CPT's feasibility and efficacy will be examined in 20 adolescents suffering from CA or PA-related PTSD in a multicenter study (3 sites).Patients will be assessed prior to (t0), post (t1) and 6 weeks after treatment (t2). Assessments include Clinician Administered PTSD Scale (CAPS), UCLA PTSD Index (UCLA), Beck Depression Inventory (BDI), Adolescent Dissociative Experiences Scale (A-DES), and Borderline Symptom List (BSL-23).

Detailed Description

The aim of this pilot study is to evaluate the developmentally adapted cognitive processing therapy (D-CPT)in adolescents suffering from childhood sexual abuse (CA) or childhood physical abuse (PA) related PTSD. D-CPT's feasibility and efficacy will be examined in 20 adolescents suffering from CA or PA-related PTSD in a multicenter study in Berlin, Frankfurt and Ingolstadt in Germany (3 sites).Patients will be assessed prior to (t0), post (t1) and 6 weeks after treatment (t2). Assessments include Clinician Administered PTSD Scale (CAPS), UCLA PTSD Index (UCLA), Beck Depression Inventory (BDI), Adolescent Dissociative Experiences Scale (A-DES), and Borderline Symptom List (BSL-23).

Study Timeline

• Study Start: 2012-11
• Study First Submitted: 2013-03-19
• Study First Submitted QC: 2013-06-03
• Study First Posted: 2013-06-06
• Primary Completion: 2014-03
• Study Completion: 2015-10
• Status Verified: 2016-05
• Last Update Submitted: 2016-05-23
• Last Update Posted: 2016-05-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 12

Inclusion Criteria

• PTSD after CSA and/or CPA beyond the age of three (confirmed by a structured clinical interview, CAPS-CA, German Version IBS-KJ)
• PTSD must be the primary diagnosis (most severe disorder according to SCID)
• age 14 - 21 years
• living in safe conditions
• informed consent from parents/legal guardians (if under 18) and participant

Exclusion Criteria

• current psychotic
• substance related or organic mental disorder
• acute suicidality, severe medical conditions
• mental retardation
• insufficient knowledge of German language.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
DCPT	Developmentally adapted cognitive processing therapy	Treatment with developmentally adapted D-CPT. 30 to 36 individual treatment sessions. Treatment sections comprise a commitment phase (5 sessions), emotion regulation phase (6 sessions), CPT (15 sessions) and a final phase targeting developmentally-related challenges (4 sessions).

Primary Outcome Measures

Name	Time	Method
Clinician-Administered PTSD-Scale for Children and Adolescents	t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up

Secondary Outcome Measures

Name	Time	Method
UCLA PTSD Index (UCLA)	t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up
Beck Depression Inventory	t0=pretreatment (baseline), t1= change from baseline at post-treatment after 20 weeks t2= change from posttreatment at 6 weeks follow-up

Trial Locations

Locations (1)

Department of Clinical Psychology and Psychotherapy, Goethe University; 🇩🇪 Frankfurt, Hessen, Germany