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临床试验/NCT05005871
NCT05005871已完成不适用

Comparison of the Effectiveness of Intramuscular and Transmucular Quadratus Lumborum Blocks Quality in Postoperative Pain

Udayana University2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2021年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
48
试验地点
2
主要终点
Postoperative pain

研究概览

简要总结

Acute pain is reported in approximately 80% of patients undergoing postoperative care for various types of surgical procedures in the United States. Another study reported patient postoperative pain intensity with 75% with severe pain in the first 1 to 2 postoperative days and 38% reporting moderate to severe pain at 14 postoperative days. Several modalities have been used as the standard for the management of pain postoperative C-sections.

One of the postoperative analgesic modalities for SC is quadratus lumborum block (QLB). This technique has advantages in relieving postoperative pain after C-section because it is considered to be able to relieve visceral pain as well as somatic pain. The transmuscular QLB (QLBT) approach is one of the most frequently used. This technique was found to be effective with regard to the distribution of analgesics to the paravertebral spaces which is the hallmark of QLB. However, this technique was found to be difficult to perform. Difficulties were reported related to the position of the procedure i.e. lateral or sitting position.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Underwent C-section with subarachnoid block
  • Aged 18-35 years old.
  • ASA preoperative physical status 1-2

排除标准

  • Coagulopathy
  • Anatomic abnormalities of the abdomen
  • History of allergy to local anesthesia
  • History of hyperalgesia
  • History of drug abuse (sedatives, opioids, paracetamol, or other pain relievers)
  • Require postoperative intensive care
  • Refuse to participate in research.

结局指标

主要结局

Postoperative pain

时间窗: Up to 24 hours after surgery

Postoperative pain intensity measured by Visual Analog Scale (VAS), 0=no pain, 100=worst pain

Postoperative morphine requirements

时间窗: Up to 72 hours after surgery

Total delivered morphine dose after surgery to alleviate postoperative pain (measured by total delivered dose recorded on the Patient-Controlled Analgesia tool)

次要结局

未报告次要终点

研究者

发起方
Udayana University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Christopher Ryalino, MD

Principal Investigator

Udayana University

研究点 (2)

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