Controls and Healthy Vasculature Initiative
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 1,000
- 试验地点
- 2
- 主要终点
- To collect samples from healthy volunteers to establish and validate technical assays and normal physiologic mechanisms and parameters for on-going and future basic and translational research studies.
研究概览
简要总结
Background:
Diseases involving blood, blood vessels, and immune systems are leading causes of death in the United States. Researchers studying these diseases need to compare blood samples from both healthy and sick individuals. Blood samples from healthy people are also used to establish what is normal when developing new tests for diseases and to make sure new testing equipment is working properly.
Objective:
This natural history study will collect blood samples from healthy people. The blood will be used for various kinds of research.
Eligibility:
Healthy adults aged 18 years or older. Pregnant or nursing women will be excluded.
Design:
Participants will have a telehealth visit or telephone call to review their medical history.
They will come to the NIH Clinical Center. They will have a needle inserted into a vein in their arm or hand. About 10 tablespoons of blood will be drawn through the needle.
Researchers may perform a complete blood count, a type of blood test that can help evaluate the participant s overall health. They may do a blood type test.
The blood samples will also be used for genetic studies.
Some blood samples may be stored for use in future research.
Participants may choose to return for repeat visits for up to 10 years. Review of their medical history may also be repeated at later visits. They will receive $50 per blood collection visit.
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详细描述
Study Description:
This study will serve to provide tissue samples from individuals with healthy vasculature for mechanistic studies of vascular inflammation and thrombosis.
Objectives:
Primary Objective:
To collect samples from healthy volunteers to:
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 90 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •INCLUSION CRITERIA:
- •In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- •Stated willingness to comply with all study procedures
- •Aged 18 years and older
- •Ability of subject to understand and the willingness to sign a written informed consent document
- •Self-reported in good general health
排除标准
- •An individual who, by self-report, meets the following criteria will be excluded from participation in this study:
- •Current pregnancy or lactation
研究组 & 干预措施
1
Healthy Adults
结局指标
主要结局
To collect samples from healthy volunteers to establish and validate technical assays and normal physiologic mechanisms and parameters for on-going and future basic and translational research studies.
时间窗: Up to 10 Years
This protocol does not have an outcome measure, but will obtain blood samples to optimize assays, conduct mechanistic investigations, measure vascular biomarkers, and facilitate the study of vascular and immunologic diseases in patients enrolled in other studies.
次要结局
未报告次要终点