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Evaluation of the effectiveness of a novel arc-shaped multichannel rectal intracavitary applicator based on pelvic MRI images for the treatment of rectal cancer

Phase 1
Conditions
Locally advanced rectal cancer or locally recurrent (without distant metastasis) rectal cancer
Registration Number
ChiCTR2400089009
Lead Sponsor
Peking University Third Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria
  1. Age > 18 years(based on the date of signing the informed consent form)<br>2. Patients with locally advanced rectal cancer or locally recurrent (without distant metastasis) rectal cancer who are suitable for afterloading brachytherapy treatment.<br>3. Patients who are able to be treated with rear-loading radiotherapy as determined by the investigator based on his/her medical history, physical examination, and vital signs<br>4. Agree to participate in this study and follow the requirements of this study
Exclusion Criteria
  1. Patients with severe cardiopulmonary insufficiency or other vital organ insufficiency.<br>2. Patients with severe bleeding tendency or coagulation disorders.<br>3. Patients with rectal perforation or other serious complications.<br>4. Patients judged by the investigator to be unsuitable to participate in this clinical study.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Incidence of adverse reactions;
Secondary Outcome Measures
NameTimeMethod
ORR;PFS;OS;LRFS;HRQoL;
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