*Implementation of a symptom based algorithm for calcium management after total thyroidectomy *

Recruiting

• Conditions: Hypocalcemia; hypoparathyroidism; low calcium bloodlevel; 10033949

• Registration Number: NL-OMON45592
• Lead Sponsor: Maasstadziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 100

Inclusion Criteria

1. Indication for total thyroidectomy or completion thyroidectomy
2. Patient age 18 years or older at the time of inclusion

Exclusion Criteria

1. Pre-operative abnormal adjusted serum calcium level (reference range 2.20 -2.55 mmol/L)
2. Hyperparathyroidism
3. Planned parathyroidectomy
4. History of epileptic seizures
5. Pregnancy
6. Non dutch speaking
7. Not able to give informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The primary study endpoint is the difference in the percentage of patients<br /><br>treated with calcium (and active vitamin D3-metabolite) supplements before and<br /><br>after implementation of the new algorithm. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Number of readmissions for intravenous calcium supplementation<br /><br>2. Number of calcium related contacts with the outpatient department<br /><br>3. The incidence of hypocalcemia: both transient and permanent<br /><br>4. Risk factors for hypocalcemia (patient or surgery related)<br /><br>5. Incidence of hypocalcemic symptoms emerging after discharge<br /><br>6. Complications related to hypocalcemia<br /><br>7. Duration of admission<br /><br>8. Number of patients requiring intravenous calcium supplementation<br /><br>9. Relation between EKG abnormalities and hypocalcemia</p><br>