Real-world Incremental Costs of Opportunistic Upper Gastrointestinal Endoscopy Added to Colorectal Cancer Screening and the Economic Burden of Gastric Cancer Management: a Retrospective Cohort Study - Study Protocol
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 250
- 试验地点
- 1
- 主要终点
- Stage distribution at diagnosis
研究概览
简要总结
Data will be extracted from routinely collected hospital databases.
详细描述
Electronic medical records; Endoscopy and pathology databases; Surgical and hospitalization records; Oncology treatment databases; Imaging and diagnostic services; Institutional mortality records.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Eligible participants were adults aged 50 to 75 years or older who had been referred for colonoscopy as part of the national colorectal cancer screening programme, following a positive FIT. To be included, individuals also needed to provide informed consent and agree to undergo an EGD endoscopy for the screening of potential upper gastrointestinal precancerous conditions or lesions.
- •Patients with gastric adenocarcinoma, diagnosed and treated at Unidade Local de Saúde do Alto Alentejo between 2015 and 2025.
排除标准
- •Exclusion criteria included a prior diagnosis of gastric cancer, as well as any condition that would prevent the safe performance of the EGD or the collection of gastric mucosal biopsies. Previous EGD was not listed as an exclusion criterion.
- •Other types of gastric tumors.
- •Gastric involvement from metastatic disease of another primary tumor.
研究组 & 干预措施
Cohort A - Opportunistic screening cohort
Cohort B - Gastric cancer cohort
结局指标
主要结局
Stage distribution at diagnosis
时间窗: At diagnosis (2015-2020)
Distribution of gastric cancer stages at diagnosis (Stage I-IV) according to TNM classification (expressed as percentage of patients per stage).
Treatment patterns
时间窗: During initial treatment period (2015-2020)
Types of treatment received by patients with gastric cancer, including surgery, chemotherapy, radiotherapy, and palliative care
Overall survival
时间窗: From diagnosis up to last follow-up (2015-2020)
Overall survival of patients diagnosed with gastric cancer (measured in months).
次要结局
未报告次要终点
研究者
Beatriz Mourato
Principal Investigator
Unidade Local De Saúde Do Norte Alentejano