NCT00571805撤回1 期
Placebo-controlled Study of Varenicline Effects on Nicotine Withdrawal Followed by a Test of Smoking Topography, Reward, and Reinforcement
适应症
干预措施
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Smoking reward
研究概览
简要总结
Study of varenicline 2.0 mg/day treatment for 2 weeks with smoking test done in laboratory on Day 8 and a 1 week quit attempt from Day 8-14.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •At least 10 cigarettes/day
- •Interest in quitting smoking
- •Willgness to comply with overnight smoking abbstiennce period followed by lab smoking test
排除标准
- •Pregnancy
- •Axis I psychiatric disorder which require treatment with psychoactive medication and would make study compliance difficult.
- •Clinically significant medical condition in opinion of study clinician
- •Drug or alcohol dependence inlast 12 months
- •Use of other smoking cessation medications ot treatment progams in last 2 months
研究组 & 干预措施
1
Active Comparator
Varenicline
干预措施: varencline (Drug)
2
Placebo Comparator
placebo
干预措施: placebo (Drug)
结局指标
主要结局
Smoking reward
时间窗: laboratory test
次要结局
- 1 week abstinence induced craving and reward(Day 8, 9, 11 and 14 questionaires)
研究者
研究点 (1)
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