Functional Trunk Training in Ataxia Patients

Not Applicable

Completed

• Conditions: Ataxias, Hereditary; Ataxia, Spinocerebellar
• Interventions: Other: Routine training; Other: Functional training

• Registration Number: NCT04740359
• Lead Sponsor: Hasan Kalyoncu University

Brief Summary

The study is to examine the effect of functional trunk training on trunk control and upper extremity functions in patients with autosomal recessive ataxia.

Detailed Description

Hereditary ataxias are a group of genetic diseases characterized by slow progressive gait disturbance. In addition, coordination disorders can be seen in extremities, speech and eye movements. Atrophy is common in the cerebellum. Friedreich's ataxia, ataxia telangiectasia, ataxia with vitamin E deficiency, infantile-onset spinocerebellar atrophy and Marinesco-Sjögren syndrome are autosomal recessive hereditary ataxias. The constant main sign of autosomal recessive ataxia is progressive ataxia.

The trunk has an important role on dynamic stabilization for postural reactions and limb movements. A good trunk support enables movements in other parts of the body to occur more regularly. Trunk stabilization is important to support upper and lower extremity movements, to meet the loads, and to protect the spinal cord. The relationship between upper extremity function, daily living activities and trunk functions has been emphasized in many studies but comparative studies about the rehabilitation were very less.

This study is to evaluate the effect o functional trunk training in patients with autosomal recessive ataxia.

Study Timeline

• Study First Submitted: 2021-02-02
• Study First Submitted QC: 2021-02-02
• Study First Posted: 2021-02-05
• Study Start: 2021-02-12
• Primary Completion: 2021-09-12
• Study Completion: 2021-11-01
• Status Verified: 2023-03
• Last Update Submitted: 2023-03-01
• Last Update Posted: 2023-03-02

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Without any communication impairment (seeing, hearing, hearing),
• Have not had surgery for the upper and lower extremities in the last 6 months,
• Between the ages of 5 and 18,
• The mental level determined by the pediatrician is sufficient,

Exclusion Criteria

• Patients who want to leave the study at any stage of the study
• Patients who do not attend regular training

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Control	Routine training	Routine training; mat exercises and perturbation training
Study	Functional training	Trunk training; Functional training, mat exercises and perturbation training

Primary Outcome Measures

Name	Time	Method
The quality of life	through of te study, average 8 weeks	The Children's Quality of Life Scale (PedsQL) was used determine to quality of life level.
Trunk impairment	through of te study, average 8 weeks	The Trunk Disorder Scale (TIS) was used to assess static and dynamic sitting balance and trunk coordination
The severity of ataxia	through of te study, average 8 weeks	The International Ataxia Rating Scale (ICARS) was used to determine the severity
The Functional Independence	through of te study, average 8 weeks	The Functional Independence Scale for Children (WeeFIM) was used determine to independence level.

Secondary Outcome Measures

Name	Time	Method
Upper extremity functional performance	through of te study, average 8 weeks	The 9-Hole Peg test was used to evaluate upper extremity performance
Functional Reach Test	through of te study, average 8 weeks	Functional Reach Test was used determine to dynamic trunk balance

Trial Locations

Locations (1)

Hasan kalyoncu üniversitesi; 🇹🇷 Gaziantep, Eyalet/Yerleşke, Turkey