ISRCTN87077451已完成未知
Short term intraocular pressure trends in high risk patients following intravitreal Ranibizumab (Lucentis) injections for wet age related macular degeneration - is there a role for systemic Acetazolamide (Diamox) in those with glaucoma?
York Teaching Hospital NHS Foundation Trust (UK)0 个研究点目标入组 24 人开始时间: 2012年4月26日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 24
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Patients with neovascular (wet) AMD requiring Lucentis injections
- •2. Glaucoma
- •3. Glaucoma suspect
- •4. Written informed consent
- •5. Baseline pre-injection IOP of less than 30mmHg
排除标准
- •1. Baseline pre-injection IOP of 30 mmHg or higher
- •2. Unable to give written informed consent
- •3. Known allergy to sulphur/sulphonamide containing drugs or acetazolamide
- •4. 18 years or younger
- •5. Marked kidney or liver disease/dysfunction
- •6. Supra-renal gland failure
- •7. Hyperchloremic acidosis
- •8. Hepatic cirrhosis
- •9. Pregnancy / [Pre]-menopausal
- •10. Concomitant use of other oral carbonic anhydrase inhibitors
研究者
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Can Diamox lower the eye pressure in glaucoma or glaucoma suspect patients who are receiving eye injections for wet age related macula degeneration?Glaucoma and Glaucoma suspectMedDRA version: 14.1Level: LLTClassification code 10006028Term: Borderline glaucoma (glaucoma suspect)System Organ Class: 10015919 - Eye disordersMedDRA version: 14.1Level: PTClassification code 10018304Term: GlaucomaSystem Organ Class: 10015919 - Eye disordersEUCTR2010-023037-35-GBYork Teaching Hospital NHS Foundation Trust24
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