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Clinical Trials/NCT06738927
NCT06738927
Not yet recruiting
Not Applicable

Otological Study of Facial Cleft Patients Over 10 Years of Age (Excluding Isolated Cleft Lip)

University Hospital, Brest1 site in 1 country500 target enrollmentDecember 12, 2024

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Serous Otitis
Sponsor
University Hospital, Brest
Enrollment
500
Locations
1
Primary Endpoint
To study the otological status of patients based on the presence or absence of ENT surgical management involving the placement of transtympanic ventilatory tubes.
Status
Not yet recruiting
Last Updated
last year

Overview

Brief Summary

Studies published on the placement of transtympanic ventilatory tubes in children with cleft palate show heterogeneous results, highlighting the need for a new study with strong statistical power and long-term follow-up to clarify the real benefits of this intervention.

Mirashrafi (2022) and Maina (2022), for example, emphasize the current uncertainties regarding the management of otitis media with effusion in children with cleft palate. Mirashrafi conducted a study on 40 children and found no significant difference between those with a complete cleft palate and those with an incomplete cleft palate in terms of middle ear status after the placement of transtympanic ventilatory tubes. Maina, in an ongoing review, identified a lack of consensus on the optimal management of chronic otitis media with effusion, with outcomes being varied and often of low methodological quality.

The absence of convincing evidence justifies the need for further research to establish clear guidelines. The objective is to study the otological status of patients based on the presence or absence of ENT surgical management involving the placement of transtympanic ventilatory tubes.

Detailed Description

The primary evaluation criterion will be ENT consultations: Tympanic examination: Anatomical analysis of the tympanic membrane, assessing the presence or absence of: Serous otitis Tympanic membrane perforation Retraction pocket Cholesteatoma Otorrhea Myringosclerosis Tympanosclerosis Audiometric tests: Assessment of auditory results from bone and air conduction curves for frequencies ranging from 250 to 4000 Hz, with analysis at every 250 Hz.

Registry
clinicaltrials.gov
Start Date
December 12, 2024
End Date
December 12, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Presence of a facial cleft between 2004 and 2014 Minor and adult patients Followed up by ENT services at the University Hospital of Brest or Marseille

Exclusion Criteria

  • Patients under legal protection (guardianship, curatorship, etc.) Refusal to participate Objection from one of the parents Isolated cleft lip No ENT follow-up

Outcomes

Primary Outcomes

To study the otological status of patients based on the presence or absence of ENT surgical management involving the placement of transtympanic ventilatory tubes.

Time Frame: 01/01/2004 to 01/01/2014

Study Sites (1)

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