Influence of Posture and Gas Insufflation on Perioperative Lung Function
- Conditions
- Pneumoperitoneum
- Registration Number
- NCT00948571
- Lead Sponsor
- Kliniken Essen-Mitte
- Brief Summary
Perioperative airway resistance and lung function are evaluated perioperatively in patients, who undergo surgical procedures in different postures and with or without gas insufflation into the peritoneal cavity.
- Detailed Description
Lung function, upper and lower airway resistance measurements are performed in patients in prone horizontal or head tilted down (40°) position. Half of the patients with head down position will have surgery in laparoscopic technique (including gas insufflation to achieve a pneumoperitoneum). Measurements are performed on the day prior to surgery, on the morning of surgery, 30 - 45 minutes, 2 hours, and 24 hours after extubation.
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- Patients older than 18 years of age.
- Patients with normal lung function with respect to age, gender and weight. -Patients scheduled for Prostatectomies, robotic Prostatectomies, and open hemicolectomies.
Exclusion Criteria
- Patients younger than 18 years.
- Patients with pathological lung function.
- Patients with with major cardiac disease.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement of FEV1 (forced expiratory volume in one second) and the MEF50/MIF50 ratio 18 months
- Secondary Outcome Measures
Name Time Method Changes in nasal airway resistance 18 months
Trial Locations
- Locations (1)
Prof. Dr. Harald Groeben
🇩🇪Essen, Germany