Effects of Periarticular Infiltration Analgesia during Total Knee Arthroplasty plus Percutaneous Infiltration Analgesia of the Distal Quadriceps Muscle the Day after Surgery

Not Applicable

Completed

• Conditions: Knee Osteoarthritis

• Registration Number: JPRN-jRCT1090220298
• Lead Sponsor: Makoto Sumiya

Brief Summary

A likely reason for this is that pain was successfully alleviated in Group B from postoperative day 4 without reducing the threshold for pain by controlling pain during the "3 days postoperatively when pain is considered strongest." Another likely factor is that the patients no longer experienced "fear of pain."Injecting the same periarticular cocktail as that used intraoperatively into the distal quadriceps muscle on the day after surgery induced a further, reliable analgesic effect not only on postoperative day 2 but also 2 weeks postoperatively.The most important aspect of the present study is that the second injection was administered immediately while the effect of the intraoperative analgesic cocktail persisted and while pain was not severe. Furthermore, a strong analgesic effect was observed from the second injection in patients who did not consider the effect of the initial intraoperative injection particularly strong. Although intraoperative analgesic injections can sometimes leak into the joint, the postoperative injection does not leak inside or outside the joint. The probability of a reliable analgesic effect is therefore strong. In conclusion, an additional injection to the distal quadriceps muscle the day after surgery with an intraoperative periarticular injection resulted in a significant reduction of pain from the second postoperative day and permitted many patients to walk the day after surgery.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2015-04-23
• Study Start: 2017-06-15
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

The author, who is an orthopedic specialist, investigated all the patients personally. Patients who underwent unilateral TKA for the first time at the same facility (a general hospital) during the 1-year period from May 2014 to April 2015 were included in the study.

Exclusion Criteria

Patients were excluded if they had undergone simultaneous bilateral TKA or had a history of patellar resection. Patients using narcotic analgesics and those with acute or chronic prosthetic joint infection, mental disorders, Charcot's joint, or systemic illnesses such as a neuromuscular disorder or blood coagulation disorders were also excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
10-point visual analog scale (VAS)

Secondary Outcome Measures

Name	Time	Method
knee range of motion for one week later and two weeks later<br>hosupitalization