Iodine Supplement Strategies Between Routine Iodine Supplementation and Selective Iodine Supplementation

Not Applicable

Completed

• Conditions: Pregnancy Related; Iodine Deficiency
• Interventions: Dietary Supplement: Triferdine/Ferli-6; Dietary Supplement: Triferdine

• Registration Number: NCT03078140
• Lead Sponsor: Chiang Mai University

Brief Summary

Pregnant women who attend at our antenatal clinic will random to 2 groups. First will receive routine iodine supplementation. The other will receive iodinated pill or only iron supplementation base on their urine iodine status.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-02-27
• Study First Submitted QC: 2017-03-07
• Study First Posted: 2017-03-13
• Study Start: 2017-05-01
• Primary Completion: 2018-04-30
• Study Completion: 2018-05-31
• Status Verified: 2018-10
• Last Update Submitted: 2018-10-09
• Last Update Posted: 2018-10-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 208

Inclusion Criteria

• first visit for antenatal care in the first trimester
• singleton pregnancy
• delivered at Maharaj Nakorn Chiangmai Hospital

Exclusion Criteria

• thyroid disease which diagnosed before pregnancy or currently
• history of thyroid gland surgery or iodine ablation therapy
• received iodine supplement before pregnancy
• received any medication for thyroid disease treatment, within 6 weeks postpartum women or breast feeding period
• family history of thyroid disease
• having underlying disease or contraindication which cannot received iodine supplement
• loss follow-up or incomplete data.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Triferdine/Ferli-6	Triferdine/Ferli-6	Triferdine or ferli-6 1 tablet by mouth daily base on iodine status. The supplement will give after 1st trimester until delivery
Triferdine	Triferdine	Triferdine 1 tablet by mouth daily. Start after 1st trimester until delivery

Primary Outcome Measures

Name	Time	Method
iodine status	at delivery	mean urine iodine

Trial Locations

Locations (1)

Kuntharee Traisrisilp; 🇹🇭 Chiang Mai, Thailand