Diabetic Complications and Obstructive Sleep Apnea in Type 2 Diabetic Patients: A Longitudinal Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 330
- 试验地点
- 1
- 主要终点
- the new onset and types of tumor in T2DM patients
研究概览
简要总结
To follow up the progress of chronic complications in T2DM patients who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018.
详细描述
Obstructive sleep apnea (OSA) is a common chronic sleep disorder and a frequent comorbidity in patients with type 2 diabetes. There has been increasing recognition that OSA is highly prevalent in persons with type 2 diabetes. This study is to explore the relationship between OSA and the progress of chronic diabetes-related complications in type 2 diabetes who had undergone anthropometric measurements, laboratory testing and standard overnight polysomnography monitor from 2013 to 2018 in the Department of Endocrinology and Diabetes, The First Affiliated Hospital of Xiamen University, Xiamen, China.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Type 2 diabetes
- •Age：18-80
排除标准
- •Patients with non type 2 diabetes mellitus
- •Preparation for pregnancy
- •Lactation patients
- •Patients with uncontrolled thyroid disease
- •Patients with severe cardiovascular disease
- •Patients with severe hepatic and renal insufficiency
- •Patients with oral and maxillofacial malformations and upper respiratory tract malformations
- •Patients with pulmonary infection or COPD
- •Patients who are not willing to accept the questionnaire survey
- •Unable to sign informed consent
结局指标
主要结局
the new onset and types of tumor in T2DM patients
时间窗: From January 1, 2013 to December 31, 2020
the new onset and types of tumor in T2DM patients
the progress of diabetic complications
时间窗: From January 1, 2013 to December 31, 2020
Diabetic complications include diabetic microvascular complications, atherosclerotic cardiovascular disease(ASCVD), and Diabetic foot disease. Diabetic microvascular complications include diabetic nephropathy, diabetic retinopathy and diabetic neuropathy. Diabetic macrovascular complications refer to ASCVD, which is defined as coronary heart disease (CHD; acute and silent MI, and unstable angina), ischemic stroke, or peripheral artery disease (PAD).
次要结局
未报告次要终点