IRCT20130811014330N9
Recruiting
Phase 3
The use of human stromal vascular fraction(SVF) and platelet-rich plasma(PRP) in treatment of therapy-resistant diabetic foot ulcers: a randomized control trial phase III
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Mashhad University of Medical Sciences
- Enrollment
- 20
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Having a diabetic ulcer grade 1 to 4 according to Wagner's classification
- •Having a single wound in the legs and extremities (fingers, soles, heels, on the toes) that has been at least 4 weeks old
- •No smoking, alcohol and drug addiction
- •Not taking drugs that may interfere with wound healing, such as corticosteroids, immunosuppressive agents, and cytotoxic agents
- •Not having concurrent diseases such as cancers, vasculitis, kidney and liver failure, and heart failure that may cause problems in wound healing
- •Informed consent of patients
Exclusion Criteria
- •Patients with acute bone inflammation or osteomyelitis
- •A wound with visible bone in the target area of treatment
- •Infected diabetic foot ulcers
- •Charcot deformity
- •History of treatment with chemotherapy drugs or radiation therapy in 3 months before the start of treatment
- •Hemoglobin less than 10mg/dL
- •History of treatment with growth factors during two weeks before starting treatment
- •Patients with less than 100,000 platelets
- •Vascular problems should not be observed in the wound (not ABI?0\.7\)
Outcomes
Primary Outcomes
Not specified
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