Randomized comparative clinical trial to evaluate the efficacy of Chaturbeeja Churna with and without Rajaswala Paricharya on Premenstrual Syndrome

This study is a Prospective,Randomized,Open-label,ComparativeClinicalT****rial designed to evaluate the efficacy of Chaturbeeja Churna with and without Rajaswala Paricharya in the management of Premenstrual Syndrome (PMS). A total of 100 women aged 18–45 years**,** fulfilling PMS diagnostic criteria as per the American College of Obstetricians and Gynecologists, will be randomly allocated into two groups.

The intervention will be administered over three consecutive menstrual cycles**.**Group A will receive oral Chaturbeeja Churna along with Rajaswala Paricharya, while Group B will receive Chaturbeeja Churnaalone. The primary outcome will be assessed using the **Daily Record of Severity of Problems (DRSP)**scale. Secondary outcomes will include assessment of quality of life using the WHOQOL-BREF scale and evaluation of inflammatory markers **(CRP and ESR).**Safety will be monitored by documenting adverse drug reactions throughout the study.

The study aims to assess the comparative efficacy and additional benefit of Rajaswala Paricharyawhen used alongside Chaturbeeja Churna in PMS management.