DRKS00017570招募中2 期
Focal radiation dose escalation in patients with primary prostate cancer (HypoFocal) – a prospective, multicenter, non-randomized study with 2 arms / Accompanying translational project: PersoRad - HypoFocal - Phase II
niversitätsklinikum Freiburg, Klinik für Strahlenheilkunde0 个研究点目标入组 130 人开始时间: 2019年8月23日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 招募中
- 发起方
- 入组人数
- 130
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomized controlled study
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 one（—）
- 性别
- Male
入选标准
- •Histology proven PCA; - cT1b-3b, cN0 and cM0 (MRI, PET/CT); -Intermediate and high risk; - ECOG Performance Status 0 or 1; - IPSS < 15;
- •- size of prostate gland = 60 ml (after concluding neoadjuvant ADT)
排除标准
- •- cT4 (MRT or PET/CT); - Gleason = 9; - Neuroendocrine tumors; - PSA > 40 ng/ml; - Contraindications for MRI; - Other malignancies (tumors that have not been healed); - Fluorides, inflammatory bowel disease; - Previous TURP or surgery of the prostate; - Patient not legally competent; - Previous radiation in the pelvic area
研究者
相似试验
招募中
3 期
Image-guided focal dose escalation in patients with primary prostate cancer treated with primary external beam hypofractionated radiation therapy (HypoFocal) – a prospective, multicenter, randomized phase III study.Prostate CancerDRKS00022915niversitätsklinikum Freiburg374
进行中（未招募）
1 期
Study of radiotherapy dose escalation with Intensity Modulated Radiation Therapy (IMRT) and synchronous Cetuximab for intermediate stage head and neck cancer - INTENSEEUCTR2007-000741-36-GBChristie Hospital NHS Trust28
进行中（未招募）
不适用
Pilot study of dose-escalated radiotherapy with PET/CT based treatment planning in combination with induction and concurrent chemotherapy in locally advanced (uT3/T4) squamous cell cancer of the esophagus - SPOTPhase II study of dose-intensified radiation therapy based on PET/CT-Planning in combination with induction- and concurrent chemotherapy in locally advanced squamous cell carcinomas (uT3/T4) of the esophagusEUCTR2005-006097-10-DEniversitätsklinikum Essen41
已完成
2 期
Dose-escalation by boosting radiation dose within the primary tumor on the basis of a pre-treatment FDG-PET-CT scan in stage IB, II and III NSCLC: A randomized phase II trialnon-small cell lung carcinom10038666lung cancerNL-OMON43597Antoni van Leeuwenhoek Ziekenhuis160
已完成
1 期
Phase I radiaition dose escalation study of intensity-modulated radiotherapy with end-exhalation breath-hold technique, combined with full-dose gemcitabine for patients with locally advanced pancreatic cancer.Pancreatic cancerJPRN-UMIN000004589Department of Therapeutic Radiology, Kyoto University Hospital18