Condensed Nanofat Grafting for Treatment of Androgenetic Alopecia

Not Applicable

Completed

• Conditions: Androgenic Alopecia
• Interventions: Procedure: Nanofat grafting

• Registration Number: NCT03506503
• Lead Sponsor: Jinan University Guangzhou

Brief Summary

Nowadays, multiple treatment modalities have been applied clinically to treat androgenic alopecia, such as Follicular unit transplantation(FUT), finasteride, platelet-rich plasma injection(PRP), etc. In this clinical trial, the investigators aim to analyze the effect of nanofat grafting on treating androgenic alopecia in male.

Detailed Description

The investigators will treat the hair loss area of a patient by processed nanofat grafting. The participants were asked to come back 1、3、6、9、12 months after treatment for further follow-up.

Before and after the treatment, the hair and follicular will be assessed subjectively by satisfaction assessment, dermatoscope.

Study Timeline

• Study First Submitted: 2018-04-14
• Study First Submitted QC: 2018-04-23
• Study First Posted: 2018-04-24
• Study Start: 2019-02-27
• Primary Completion: 2020-02-27
• Study Completion: 2020-05-01
• Status Verified: 2021-02
• Last Update Submitted: 2021-02-17
• Last Update Posted: 2021-02-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 10

Inclusion Criteria

• Male patients with androgenic alopecia aging from 18 to 50.
• No scars and wounds on the alopecia area.
• No skin disease or serious cardiovascular disease.
• Preoperative examinations remain healthy.

Exclusion Criteria

• Serious chronic heart, liver, kidney, blood system disease
• Allergic diseases, skin inflammation or wounds
• Alopecia but not androgenic alopecia
• Acute or chronic infection
• Take anticoagulant drugs
• Active vitiligo, psoriasis, systemic lupus erythematosus

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
processed Nanofat grafting	Nanofat grafting	processed autologous Nanofat will be injected into the area of the scalp with androgenic alopecia.

Primary Outcome Measures

Name	Time	Method
Dermatoscope	Baseline and at1,3,6,9,12 months after the treatment	the density of hair follicle and diameter of hair will be analized by dermatoscope before and after the treatment of Nanofat grafting.

Trial Locations

Locations (1)

the first affiliated hospital of Jinan University; 🇨🇳 Guangzhou, Guangdong, China