Snow Properties and Its Modeling for Studying Gas Exchange Under the Simulated Avalanche Snow
试验速览
- 阶段
- 不适用
- 入组人数
- 45
- 试验地点
- 4
- 主要终点
- The length of breathing
研究概览
简要总结
The aim of the study is to investigate respiratory parameters of a person in the simulated avalanche snow and consequent use of the measured data for development of a mathematical-physical model of breathing during increasing hypercapnia in the avalanche.
详细描述
The study is a part of a university research project aimed at studying physiological conditions and development of breathing parameters of a person breathing in the simulated avalanche snow. Presence of an air pocket and its size play an important role in survival of victims buried in the avalanche snow. Even small air pockets facilitate breathing, yet they do not provide a significant amount of fresh air for breathing. The investigators hypothesize that the size of the air pocket significantly affects the airflow resistance and work of breathing. The aim of the study is to investigate the effect of the air pocket volume on gas exchange and work of breathing in subjects breathing into the simulated avalanche snow.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy and fit volunteers, classified as The American Society of Anesthesiologists class I
- •without a smoking history
排除标准
- •Tiffeneau Index less than 0.70
- •any cardiovascular or respiratory condition
结局指标
主要结局
The length of breathing
时间窗: Continuously within 30 minute interval from the beginning of the breathing experiment
Time to termination of the breathing experiment due to the decision of the tested subject, or determined by high end-tidal carbon dioxide value or by the order by the clinician assessing the health status of the subjects.
次要结局
未报告次要终点