临床试验/NCT00333151

NCT00333151已完成3 期

Effect on Glycemic Control of Liraglutide in Combination With Rosiglitazone Plus Metformin Versus Rosiglitazone Plus Metformin in Subjects With Type 2 Diabetes

Novo Nordisk A/S89 个研究点分布在 1 个国家目标入组 576 人开始时间: 2006年5月1日最近更新: 2017年1月25日

适应症

试验速览

阶段: 3 期
状态: 已完成
发起方: Novo Nordisk A/S
入组人数: 576
试验地点: 89
主要终点: HbA1c

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

This trial is conducted in the United States of America (USA) and Canada. This trial is designed to show the effect of treatment with liraglutide when added to existing rosiglitazone and metformin combination therapy and to compare it with the effects of therapy with rosiglitazone and metformin alone.

研究设计

研究类型: Interventional
分配方式: Randomized
干预模型: Parallel
主要目的: Treatment
盲法: Double (Participant, Investigator)

入排标准

年龄范围: 18 Years 至 80 Years（Adult, Older Adult）
性别: All
接受健康志愿者: 否

入选标准

•Type 2 diabetes
•Treated with oral anti-diabetic (OAD) drugs for at least 3 months
•Treated with one or more OAD and in moderate to poor glycemic control
•Body Mass Index (BMI) less than or equal to 45.0 kg/m2

排除标准

•Treatment with insulin within the last three months prior to the trial except due to intercurrent illness, at the discretion of the Investigator
•Any serious medical condition
•Treatment with any drug that could interfere with glucose level

结局指标

主要结局

HbA1c

时间窗: after 26 weeks of treatment

次要结局

Glycaemic control
body weight
Safety and tolerability

研究者

发起方

Novo Nordisk A/S

申办方类型

Industry

责任方

Sponsor

研究点 (89)

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